Bone metastasis is a condition where cancer cells from primary tumors in other parts of the body spread to the bones, leading to the formation of secondary tumors. This condition is common in cancers such as breast, prostate, lung, and kidney cancer. Bone metastasis can cause severe pain, fractures, and other complications that significantly impact a patient's quality of life. Treatment options for bone metastasis include surgery, radiation therapy, chemotherapy, and targeted therapy. Research in bone metastasis focuses on understanding the mechanisms of cancer cell migration to the bones, developing new treatment strategies, and improving the management of bone metastasis-related complications.